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Role of GATA4/6 knockdown on luteotropic receptor expression. Control (C) or PRcre:Gata4/6f/f (G4/6) mice were treated with 7.5 IU of eCG for 48 h followed by treatment with 7.5 IU of hCG for 36, 48, 72, or 96 h. Total RNA was isolated from the corpus luteum of the C or G4/6 female mice treated with hCG for 96 h. Quantification of gene expression of Lhr and Prlr was performed using quantitative PCR (*P < 0.05, **P < 0.01, ***P < 0.001 vs. C, t-test, n = 8).
