Table 2.
Baseline characteristics by ARRA1 biomarker availability
| With biomarker (n=224) |
Without biomarker (n=225) |
p-value* | |
|---|---|---|---|
| Age (years) | 49.7(46.9–54.4) | 48.4(44.9–53.2) | 0.002 |
| Race (%) | 0.016 | ||
| White | 79.5 | 88 | |
| Black | 17 | 8 | |
| Hispanic | 3.6 | 4 | |
| Center (%) | <0.001 | ||
| Baltimore | 30.8 | 26.7 | |
| Chicago | 25.9 | 14.7 | |
| Pittsburgh | 18.3 | 16.4 | |
| UCLA | 25 | 42.2 | |
| Smoking Status (%) | 0.002 | ||
| Current | 29.9 | 18.7 | |
| Past | 49.1 | 47.1 | |
| Never | 21 | 34.2 | |
| BMI (%) | 0.400 | ||
| <20 kg/m2 | 4.5 | 3.1 | |
| 20 – 24.9 kg/m2 | 46.9 | 40.9 | |
| 25 – 29.9 kg/m2 | 35.3 | 38.7 | |
| ≥ 30 kg/m2 | 13.4 | 17.3 | |
| HCV infection (%) | 11.6 | 0.9 | <0.001 |
| History of diabetes (%) | 8 | 5.3 | 0.252 |
| Morning blood draw (%) | 62.5 | 66.7 | 0.356 |
| Free testosterone (FT, ng/dL) | 66.1(52.4–81.5) | 70.3(58.5–87.3) | 0.011 |
| Number of FT measurements contributed | 4(3–5) | 4(3–5) | 0.331 |
| Years from first FT to last FT measurements | 5.5(2.9–9.4) | 7.5(3–9.5) | 0.155 |
| HIV-positive (%) n | 77.7 (n=174) | 3.6 (n=8) | <0.001 |
| Nadir CD4 count (cells/mm3) | 223(149–336) | 242(129–375) | 0.806 |
| Current CD4 count (cells/mm3) | 372(236–528) | 307(235–589) | 0.847 |
| HIV RNA < 400 copies/ml (%) | 64.2 | 87.5 | 0.265 |
| Cumulative years on HAART | 0.29(0.12–0.47) | 0.35(0.19–0.49) | 0.655 |
| History of AIDS (n) | 16 | 1 | 0.753 |
Data are reported as median (interquartile range) or percentage.
*
By the non-parametric Wilcoxon test or Chi-square or Fisher exact test, as appropriate.