Fig. 1.

Muta™Mouse lacZ mutagenicity results for 9 PAHs in bone marrow (BM), liver (Lv), glandular stomach (GS), small intestine (SI), and lung (Lg). Plots show results for (A) benzo(a)pyrene, (B) benz(a)anthracene, (C) dibenz(a,h)anthracene, (D) benzo(b)fluoranthene, (E) chrysene, (F) benzo(k)fluoranthene, (G) indeno(1,2,3-c,d)pyrene, (H) benzo(g,h,i)perylene, and (I) dibenzo(a,l)pyrene. Mutant frequencies ± standard error are displayed for each tissue and dose. Statistical results for the overall dose–response relationship are presented for each tissue. Results of the custom contrasts for each dose vs. control are marked with an *, indicating significance at p < 0.05. Ŧ: dose–response data were truncated prior to X² analysis. NS indicates not significant.