Table 1.
Description of chemicals, doses, animal ages at the commencement of exposures, and data sources for the analyses presented in this work.
| Compound | CAS # | Purity | Dose (mg/kg BW/day) |
Animal age | Data source | ||
|---|---|---|---|---|---|---|---|
| Low | Med | High | |||||
| BaP | 50–32-8 | 99% | 25 | 50 | 75 | 25 weeks | Lemieux et al., 2011, Labib et al., 2012 |
| BaA | 53–55-3 | 99% | 20 | 40 | 80 | 10 weeks | This studya |
| DBahA | 53–70-3 | ≥ 98% | 6.25 | 12.5 | 25 | 10 weeks | Malik et al., 2013 (lacZ and DA in Lv), this studya |
| BbF | 205–99-2 | ≥ 98% | 25 | 50 | 100 | 16 weeks | This studya |
| CHRY | 218–01-9 | ≥ 98% | 20 | 40 | 80 | 14 weeks | This studya |
| BkF | 207–08-9 | ≥ 98% | 25 | 50 | 100 | 11 weeks | This studya |
| INDENO | 193–39-5 | ≥ 98% | 12.5 | 25 | 50 | 13 weeks | This studya |
| BghiP | 191–24-2 | ≥ 98% | 6.25 | 12.5 | 25 | 10 weeks | This studya |
| DBalP | 191–30-0 | ≥ 98% | 0.2 | 0.6 | 2 | 12 weeks | This study |
DA: DNA adducts; Lv: liver.
a
Mutation and DA data for lung only published in Labib et al. (2015).