Figure 5.

Reproducibility of fat measurements by 1H-MRS (hepatic fat fraction, HFF) obtained from in vivo livers before ethanol intoxication (left box plot), after ethanol intoxication (middle box plot), and ex vivo livers (right box plot) (n=20, for each group). In the pre-ethanol group mean HFF was 0.69% (SD, ±0.33%; P = 0.7483). After ethanol intoxication in vivo measurements showed a mean of 5.8% (median of 4.1% (IQR, 2–15 U/l; P = 0.002) and for ex vivo livers 5.67% (SD, ±2.09%; P = 0.0543).

*Significant difference between pre- and post-ethanol HFF measured in vivo (P = 0.0029), as well as pre- and post-ethanol HFF measured ex vivo (P < 0.001).