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. Author manuscript; available in PMC: 2017 Jan 21.
Published in final edited form as: Lab Chip. 2016 Jan 21;16(2):334–344. doi: 10.1039/c5lc01353d

Figure 5.

Figure 5

Soluble factors in culture. (A) Concentration of IL-6 isolated from HS-5-seeded bone-like scaffolds cultured in device taken from the interface well at 24 and 48 hours of culture. Error bars represent the SEM of 3–4 wells. (B) Plot of normalized concentration for simulated diffusion in the device at several time points over 24 hours. The initial concentration of solute was localized to the volume occupied by the bone-like scaffold at time = 0 h. The solute simulated was approximately 10 kDa with a diffusion coefficient of 100 μm2/s.