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. Author manuscript; available in PMC: 2016 Jan 14.
Published in final edited form as: FEBS Lett. 2011 Dec 9;586(1):60–63. doi: 10.1016/j.febslet.2011.11.024

Figure 4. Binding model of tRNA to SepCysS.

Figure 4

The crystal structure of AfSepCysS (PDB: 2E7J [8]) was superimposed onto the structure of human SepSecS complexed with tRNASec (PDB: 3HL2 [13]) using PylMOL (Molecular Graphics System, Version 1.0, Schrödinger, LLC). Residue Lys345 is close to the phosphate backbone of the tRNA 3′-end and is critical for the activity of SepCysS. The Sep moiety and A76 of the tRNA are missing in the structure.