Table 1.
Mj SepCysS | Af numbering | Relative activity | Mj SepCysS | Af numbering | Activity |
---|---|---|---|---|---|
WT | 100 ± 0 | S231A | S206 | 0 ± 0 | |
C64S | C39 | 0 ± 0 | H233A | H208 | 0 ± 0 |
C67S | C42 | 0 ± 0 | K234R | K209 | 0 ± 0 |
R96A | R73 | 89 ± 27 | K265A | K240 | 0 ± 0 |
R102A | R79 | 0 ± 0 | C272S | C247 | 0 ± 0 |
H126A | H103 | 0 ± 0 | R292A | R267 | 99 ± 51 |
Y127A | Y104 | 35 ± 17 | H325A | H300 | 124 ± 28 |
D182A | D157 | 107 ± 22 | K354A/R356A | K329/R331 | 92 ± 47 |
N187A | N162 | 85 ± 17 | K370A | K345 | 33 ± 22 |
N208A | N183 | 101 ± 24 |
SepCysS activities were determined using a benzyl viologen assay. Relative activities were assigned to SepCysS variants based on the color intensity of three repeats with standard deviations indicated.