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. Author manuscript; available in PMC: 2016 Jan 14.
Published in final edited form as: Clin Genet. 2000 Sep;58(3):209–215. doi: 10.1034/j.1399-0004.2000.580308.x

Table 3.

Assays of genomic instability and DNA repair capacity in RTS*

Induced DNA repair Chromosome instability SCE Somatic mutation
Ultraviolet light Ionizing radiation Spontaneous MMC Diepoxybutane Bleomycin Ionizing radiation Spontaneous MMC Spontaneous
Literature Decreased [4] (21–23) Increased [2] (26) Increased [1] (19) (fibroblasts) Increased [1] (27) Normal [2] (18) Increased [2] (28) Increased [1] (29) Normal [1] (30) (HPRT)
Normal [2] (24, 25) Normal [2] (26) Normal [4] (18, 19) (lymphocytes) Normal [2] (18) Normal [1] (18)
Our patient Normal Normal Normal Normal Normal Normal Normal [?] (GPA)
*

Numbers of patients are in square brackets and reference numbers are in round brackets.