Table S1.
Timing of the physical and mental examinations
| M0 | M1 | M2 | M3 | |
|---|---|---|---|---|
| Intolerance | ○ | ○ | ○ | ○ |
| Blood test* | ○ | ○ | ○ | ○ |
| Serum ketone bodies** | ○ | ○ | ○ | ○ |
| ADAS-Jcog | ○ | ○ | ○ | ○ |
| MMSE | ○ | ○ | ○ | ○ |
Notes:
*
Hemogram, liver function (alanine aminotransferase and aspartate aminotransferase), renal function (creatinine and urea nitrogen), nutrition status (glucose, glycohemoglobin A1C, low-density lipoprotein and high-density lipoprotein, triacylglycerol, albumin, and total protein), electrolytes (sodium, chloride, and potassium);
**
acetoacetic acid and β-hydroxybutyric acid.
Abbreviations: M, month; ADAS, Alzheimer’s Disease Assessment Scale; MMSE, Mini-Mental State Examination; ADAS-Jcog, ADAS cognitive subscale, Japanese version.