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. 2016 Jan 8;11:179–201. doi: 10.2147/IJN.S97286

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© 2016 Archibald et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Effect of sorafenib, nilotinib, SMA-Sor, SMA-Nilo, and their combination on apoptosis PC3 (A) and LNCaP cells (B) were treated for 48 hours with free or micellar sorafenib 2.5 μM and/or nilotinib 3 μM.

Notes: SMA and DMSO were used as controls. Data are expressed as mean ± SEM (n=3). ^*P<0.05 compared to control, ^**P<0.05 comparing free drug versus micellar treatments, and ^***P<0.05 comparing of free drug versus combination treatments.

Abbreviations: SMA, poly(styrene-co-maleic) acid; DMSO, dimethyl sulfoxide; SEM, standard error of the mean.