Table 2.

Naturalistic studies of pharmacological treatment of ADHD in adults ≥50 years

Author	N	Mean age (years)	Pharmacologic treatment	Doses
Manor et al60	11	62	All patients treated with MPH and at least 2 months, eight showed improvement	MPH IM 20–35 mg (N=8) MPH LA 60–80 mg (N=2) OROS MPH 72–108 mg (N=1)
Brod et al47	24	66	All patients had been taking ADHD medication at some time, and most patients reported a beneficial effect of medication
Lensing et al53	149	56	88% of the participants had been treated with ADHD medication at some time following diagnosis, and 64% used some type of ADHD medication 5 years after diagnosis	Self-reported mean daily dose: MPH 54.1 mg (range: 8–135 mg) Amphetamine 29.5 mg (range: 4–50 mg)

Abbreviations: ADHD, attention-deficit/hyperactivity disorder; MPH IM, methylphenidate immediate release; MPH LA, methylphenidate long acting; MPH, methylphenidate; OROS, osmotic-release oral system.