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. 2016 Feb;57(2):176–182.

Table 2.

Veterinary Cooperative Oncology Group criteria for grading adverse allergic and hypersensitivity events

Grade 1 2 3 4 5
Clinical signs Transient urticaria Rash; urticaria; dyspnea Symptomatic hypotension, with or without urticaria; parenteral medications necessary; edema Anaphylaxis requiring parenteral medications Death