Table 3. Allelic and genotypic distributions of FUT2 and FUT3 between UC patients and the controls.
| Genotype/allele | Controls(580) n(%) | UC (485)n(%) | OR (95%CI) | P |
|---|---|---|---|---|
| FUT2 rs281377 | ||||
| TT | 441(76.0) | 356(73.4) | ||
| TC | 126(21.7) | 114(23.5) | ||
| CC | 13(2.2) | 15(3.1) | ||
| TC+CC | 139(24.0) | 129(26.6) | 0.871(1.150–1.517) | 0.324 |
| allele C | 152(13.1) | 144(14.8) | 0.904(1.156–1.478) | 0.247 |
| FUT2 rs1047781 | ||||
| AA | 160(27.6) | 155(32.0) | ||
| AT | 314(54.1) | 247(50.9) | ||
| TT | 106(18.3) | 83(17.1) | ||
| AT+TT | 420(72.4) | 330(68.0) | 0.623(0.811–1.056) | 0.119 |
| allele T | 526(45.3) | 413(42.6) | 0.753(0.894–1.061) | 0.200 |
| FUT2 rs601338 | ||||
| GG | 575(99.1) | 479(98.8) | ||
| GA | 5(0.9) | 6(1.2) | ||
| AA | 0(0) | 0(0) | ||
| GA+AA | 5(0.9) | 6(1.2) | 0.437(1.441–4.749) | 0.547 |
| allele A | 5(0.4) | 6(0.6) | 0.437(1.438–4.726) | 0.548 |
| FUT3 rs28362459 | ||||
| TT | 332(57.2) | 281(57.9) | ||
| TG | 219(37.8) | 174(35.9) | ||
| GG | 29(5.0) | 30(6.2) | ||
| TG+GG | 248(42.8) | 204(42.1) | 0.761(0.972–1.241) | 0.819 |
| allele G | 277(23.9) | 234(24.1) | 0.830(1.013–1.237) | 0.895 |
| FUT3 rs3745635 | ||||
| GG | 435(75.0) | 336(69.3) | ||
| GA | 136(23.4) | 133(27.4) | ||
| AA | 9(1.6) | 16(3.3) | ||
| GA+AA | 145(25.0) | 149(30.7) | 1.016(1.330–1.742) | 0.038 |
| allele A | 154(13.3) | 165(17.0) | 1.055(1.339–1.699) | 0.016 |
| FUT3 rs3894326 | ||||
| TT | 471(81.2) | 406(83.7) | ||
| TA | 105(18.1) | 76(15.7) | ||
| AA | 4(0.7) | 3(0.6) | ||
| TA+AA | 109(18.8) | 79(16.3) | 0.611(0.841–1.156) | 0.286 |
| allele A | 113(9.7) | 82(8.5) | 0.635(0.856–1.153) | 0.305 |