Table 2.
Characteristics of patients with and without diastolic dysfunction. P-values reflect either t-tests or chi-square tests, where appropriate, unless otherwise noted
| Progression N = 43 |
No Progression N = 111 |
p-value | |
|---|---|---|---|
| Demographics | |||
| Age, mean(SD) | 62.8 (11.6) | 65.3 (9.4) | 0.1822 |
| Female, N (%) | 32 (74.4) | 92 (82.9) | 0.2341 |
| Race1, N(%) | 0.2307 | ||
| African American | 22 (51.2) | 74 (66.7) | |
| Asian | 3 (7.0) | 4 (3.6) | |
| Caucasian | 7 (16.3) | 11 (9.9) | |
| Latino | 10 (23.3) | 22 (19.8) | |
| Native American | 1 (2.3) | 0 (0.0) | |
| Physical measures | |||
| BMI, mean(SD) | 30.3 (6.6) | 30.6 (7.8) | 0.7917 |
| Systolic BP, mean(SD) | 137.6 (24.8) | 135.6 (19.3) | 0.6353 |
| Diastolic BP, mean (SD) | 73.1 (12.4) | 75.5 (11.9) | 0.2775 |
| BUN, mean (SD) | 18.5 (16.0) | 18.6 (11.3) | 0.993 |
| Creatinine, mean (SD) | 1.4 (1.7) | 1.3 (1.2) | 0.7109 |
| Hemoglobin, mean (SD) | 12.3 (1.3) | 12.8 (1.7) | 0.0603 |
| Medication use | |||
| Beta blockers, N (%) | 18 (41.9) | 42 (37.8) | 0.6461 |
| ACEI, N (%) | 29 (67.4) | 70 (63.1) | 0.6109 |
| ARB, N (%) | 26 (60.5) | 68 (61.3) | 0.9276 |
| Calcium channel blockers, N (%) | 27 (62.8) | 80 (72.1) | 0.2618 |
| Diuretics, N (%) | 18 (41.9) | 55 (49.6) | 0.3913 |
| Medical history | |||
| Smoker, N (%) | 33 (76.7) | 85 (76.6) | 0.9824 |
| Diabetes, N (%) | 24 (55.8) | 70 (63.1) | 0.4079 |
| Echocardiogram parameters | |||
| LA size, N (%) | 0.2156 | ||
| Normal | 23 (53.5) | 61 (55.0) | |
| Mild | 11 (25.6) | 38 (34.2) | |
| Moderate | 9 (20.9) | 12 (10.8) | |
| Left ventricular hypertrophy, N (%) | 19 (44.2) | 35 (61.5) | 0.1398 |
1
Fisher’s exact test