TABLE 2:
Comparison of individual tissues to a pooled normal distribution.
| Gene | Percentage (number) of SD cross-comparisons between: | |
|---|---|---|
| Individual normal tissues and pooled normal | Individual cancer tissues and pooled normal | |
| AR | 0.0 (0/7) | 33.3 (2/6) |
| BCL2 | 0.0 (0/4) | 0.0 (0/4) |
| BRCA2 | 0.0 (0/4) | 33.3 (1/3) |
| CCND1 | 50.0 (2/4) | 25.0 (1/4) |
| DCN | 0.0 (0/5) | 0.0 (0/3) |
| EGFR | 0.0 (0/6) | 0.0 (0/4) |
| ERG | 20.0 (1/5) | 33.3 (1/3) |
| ESR2 | 0.0 (0/5) | 0.0 (0/4) |
| ETV1 | 0.0 (0/5) | 0.0 (0/3) |
| FGFR1 | 28.6 (2/7) | 40.0 (2/5) |
| FGFR2 | 16.7 (1/6) | 50.0 (2/4) |
| FLI1 | 12.5 (1/8) | 92.9 (13/14) |
| FOXA1 | 0.0 (0/4) | 0.0 (0/4) |
| FUT4 | 0.0 (0/4) | 0.0 (0/3) |
| GREB1 | 25.0 (1/4) | 0.0 (0/3) |
| HOXA9 | 0.0 (0/4) | 33.3 (1/3) |
| KLK3 | 20.0 (1/5) | 25.0 (1/4) |
| LMNA | 0.0 (0/4) | 33.3 (1/3) |
| MATR3 | 0.0 (0/4) | 0.0 (0/3) |
| MMP1 | 0.0 (0/3) | 0.0 (0/3) |
| MMP14 | 0.0 (0/3) | 66.7 (2/3) |
| MMP2 | 0.0 (0/8) | 56.3 (9/16) |
| MMP9 | 10.0 (1/10) | 68.4 (13/19) |
| NPM1 | 0.0 (0/3) | 66.7 (2/3) |
| NUMA1 | 0.0 (0/4) | 50.0 (2/4) |
| PADI4/6 | 0.0 (0/6) | 16.7 (1/6) |
| PTEN | 0.0 (0/3) | 0.0 (0/3) |
| RAF1 | 37.5 (3/8) | 40.0 (2/5) |
| SATB1 | 0.0 (0/5) | 25.0 (1/4) |
| SERPINB2 | 0.0 (0/4) | 0.0 (0/4) |
| SLC45A3 | 0.0 (0/5) | ND |
| SP100 | 0.0 (0/5) | 25.0 (1/4) |
| SPDEF | 0.0 (0/5) | 0.0 (0/4) |
| TGFB1 | 25.0 (1/4) | 0.0 (0/4) |
| THBS1 | 0.0 (0/5) | 50.0 (2/4) |
| TIMP2 | 50.0 (3/6) | 28.6 (2/7) |
| TIMP3 | 66.7 (4/6) | 50.0 (2/4) |
| TMPRSS2 | 33.3 (2/6) | 75.0 (3/4) |
| VEGFA | 7.7 (1/13) | 57.1 (4/7) |
| VIM | 0.0 (0/5) | 25.0 (1/4) |
SD, significantly different, based on a KS test, p < 0.01. ND, not determined.