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. 2016 Jan 14;11(1):e0147143. doi: 10.1371/journal.pone.0147143

Fig 3. Effect of 5-HT on Energy Metabolism.

Fig 3

A, Energy expenditure, oxygen consumption, production of carbon dioxide and respiratory exchange ratio were measured for 24 h in each group mice at 21 to 23 weeks of age (n = 5–6). The acclimation time was 1 h. These values were normalized to body weight. B, The food intake of each group of mice was measured for 1 day at 17 weeks of age (n = 6). C, The rectal temperatures of each group mice at 22 weeks of age are indicated (n = 14). Data are the mean ± s.e. Data were analyzed by Student's t test (A) and two-way ANOVA (B). Columns with a different letter are significantly different (p<0.05). *p<0.05, **p<0.01 indicates significance in 5-HT-treated mice against PBS-treated mice.