Table 1. Characteristics of the randomized controlled trials included in the meta-analysis.
| Study (reference) | Country | n | Lesion size, mm | Intervention | Control | R0 A, % | R0 B, % | P value |
| Stomach (ESD) | ||||||||
| Sumiyama et al. (2014) 17 | Japan | 100 | 18.29 | Mesna | NS | 100 | 98.8 | NS |
| Kim et al. (2013) 18 | South Korea | 63 | 13.84 | SH | NS | 90.9* | 61.1* | 0.004 |
| Stomach (EMR) | ||||||||
| Yamamoto et al. (2008) 22 | Japan | 140 | 5 – 20 | SH | NS | 92.8 | 94.3 | 0.745 |
| Stomach and colon (EMR) | ||||||||
| Varadarajulu et al. (2006) 24 | USA | 60 | 22.5 | D50 | NS | 96.3 | 80.0 | 0.09 |
| Lee et al. (2006) 25 | South Korea | 72 | 17.98 | Fibrinogen | NS | 86.1 | 80.6 | 0.53 |
| Colorectal (EMR) | ||||||||
| Kishihara et al. (2012) 21 | Japan | 94 | – | SH | NS | 97.8 | 93.8 | 0.06 |
| Yoshida et al. (2012) 20 | Japan | 189 | 8.54 | SH | NS | 79.5 | 65.6 | 0.03 |
| Fasoulas et al. (2012) 26 | Greece | 49 | 46 | HES | NS | 96.0 | 95.8 | 0.94 |
| Moss et al. (2010) 27 | Australia | 80 | 37.5 | SG | NS | 90.0 | 90.0 | 1.0 |
| Katsinelos et al. (2008) 23 | Greece | 92 | 23 | D50 | NS | 93.3 | 87.2 | 0.13 |
| Hurlstone et al. (2008) 19 | UK | 163 | 19.1 | D50 | SH | 72.0 | 69.1 | > 0.01 |
R0 A, complete resection rate in active group; R0 B, complete resection rate in control group; ESD, endoscopic submucosal dissection; EMR, endoscopic mucosal resection; SH, sodium hyaluronate; NS, normal saline; D50, 50 % dextrose; SG, succinylated gelatin.
*
These proportions refer to clinical usefulness rate (complete resection within one additional submucosal injection).