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. Author manuscript; available in PMC: 2016 Jan 14.
Published in final edited form as: Curr Drug Metab. 2015;16(2):124–140. doi: 10.2174/138920021602150713114921

Table 6.

Summary of experiments describing the regulation of BCRP by genistein.

Model Genistein Concentration Treatment Duration Effect on BCRP mRNA Effect on BCRP protein References
Caco-2 cells 1–50 μM 48 h ↔ N.D. [102]
0.1–10 μM 48 h N.D. ↔ [103]
K562/BCRP cells 3–10 μM 5 days N.D. ↔ [71]
MGC-803 cells 15 μM 24 h ↓ ↔ [104]