. Author manuscript; available in PMC: 2017 Jan 1.

Published in final edited form as: Exp Gerontol. 2015 Nov 27;73:86–94. doi: 10.1016/j.exger.2015.11.017

Table 2.

Cardiovascular measurements after acute mineralocorticoid receptor antagonism with eplerenone.

	Placebo	Eplerenone
Heart rate, bpm	60±1	60±1
Systolic blood pressure, mmHg	135±4	134±4
Diastolic blood pressure, mmHg	77±2	77±2
Baseline diameter, mm	3.64±0.15	3.71±0.15
Baseline blood velocity, cm/min	24.7±2.4	23.9±1.8
Baseline shear stress, dyne/cm²	19.7±2.0	19.1±1.9
Hyperemic blood velocity, cm/min	106.5±6.3	105.2±8.7
Hyperemic shear stress, dyne/cm²	85.6±6.4	85.1±9.8
Hyperemia, %	358±20	349±24
Flow-mediated dilation, mm	0.25±0.02	0.21±0.02^*
Nitroglycerin-induced dilation, mm	0.82±0.06	0.78±0.04

Data are mean±SE.

P=0.03 vs. placebo.