Table I.

Laboratory information prior to TPE initiation

Variable	Mean	Median	Range
Weight (kg)	63.04	65.16	24 – 93
INRa	3.98	3.33	1.69 – 8.88
aPTT (seconds)a	55.06	58.2	29.6 – 86.1
Fibrinogen (mg/dL)b	206.71	194	135 – 281
AST (IU/L)	185	208	52 – 333
ALT (IU/L)	51	24	13 – 207
Alkaline phosphatase (IU/L)	81.4	30.5	1 – 333
LDHb	806.29	498	221 – 1832
Haptoglobin (mg/dL)b	9.86	7	<6 to 26
Total bilirubin/Direct bilirubina (mg/dL)	29.48/16.08	27/15.1	6.71 – 58.6 / 2.8 – 41.8
Total protein/Albumin (g/dL)	5.36/2.55	4.85/2.55	4.3 – 8.7 / 2 – 3.3
Calcium (mg/dL)a	7.98	8.1	6.8 – 8.9
Ceruloplasmin (mg/dL)	17.75	18.5	7 – 24
Hemoglobin (g/dL)	7.93	7.65	5.4 – 11.4
Platelets (K/µL)	128.5	144	41 – 203
Ammonia, serum (µM/L)c	77.38	94	12 – 136
BUN/Cr (mg/dL)c	39.38/2.42	39/1.7	7 – 82 / 0.44 – 5.7

^aOne patient missing data

^bThree patient missing data

^cTwo patient missing data