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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Lupus. 2015 Sep 18;25(2):137–154. doi: 10.1177/0961203315603139

Figure 7.

Figure 7

Relative abundance of some T cell subsets are altered and rates of apoptosis are increased in the spleens of Lck-cre transgenic (NZB × NZW)F1 mice. Representative plots displaying splenic CD4+ and CD8+ populations for non-transgenic (a) and Lck-cre transgenic (b) mice are shown. Rates of apoptosis for single positive T cells, measured by Annexin V and PI staining, are also displayed (c). The relative abundance of activated T cells is displayed as a percentage of total CD4+ cells, and for Tregs is displayed as the percentage of total cells (d). N=6–12 mice per genotype (*, p<0.05; ***, p<0.005).