Table 2.
Effects of S. frutescens on the prostate tumor development in TRAMP mice.
| TRAMP Histology Phenotype | ||||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Diet | n | Non-cancer
|
Cancer
|
|||||
| Norm | Hyp | PIN | WDC | MDC | Micro PDC | Large PDC | ||
| Control | 39 | 0 | 0 | 9(23%) | 13(33%) | 0 | 6(15%) | 11(28%)* |
| 0.05% Sutherlandia | 41 | 0 | 0 | 10(24%) | 15(37%) | 0 | 11(27%) | 5(12%)* |
| 0.25% Sutherlandia | 46 | 0 | 0 | 7(15%) | 20(43%) | 0 | 9(20%) | 10(22%) |
| 1% Sutherlandia | 37 | 0 | 0 | 9(24%) | 10(27%) | 1(3%) | 6(16%) | 11(30%) |
Chi-squared test was used to compare the large PDC incidence to the micro PDC incidence between treatment and control groups.
*
P<0.05.