Fig. 2.

Pathological findings of sorafenib-induced liver dysfunction revealed by needle biopsy. a There are fibrous thickening in Glisson’s capsules, moderate P-P bridging fibrosis, piecemeal necrosis, and ridging necrosis in part. b There are moderate hepatocytic degeneration and necrosis, lymphocytic infilterate to Glisson’s cupsule, hepatocytic balooning, and cholestasis in hepatocyte