Fig 1. Protein differential displays of AFS from ES and normal pregnant.
(A) 2D-DIGE gel stain by silver stain: Of these 12 protein spots, 5 were up-regulated and 7 were under-regulated in the ES subjects compared with the normal controls. Red arrow (spot 2, 7–9 and 10): up-regulated; Blue arrow (spot 1, 3–6 and 11–12):under-regulated. (B) 2D-DIGE images of AFS from women carrying ES and chromosomally normal fetuses: Spot 1: Vitamin D binding protein (VDBP); Spot 2: Apolipoprotein A1 (ApoA1); Spot 3–5: Alpha-1-antitrypsin(A1AT); Spot 6: Insulin-like growth factor-binding protein 1(IGFBP-1); Spot 7: Transthyretin (TTR).