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Knockdown of PFTK1 regulates activation of the PI3K/Akt signaling pathway. PANC-1 cells were infected with siRNA-PFTK1 or mock for 24 h. A. Western blot measurement of phosphorylation levels of PI3K and Akt in siRNA-PFTK1-transfected PANC-1 cells; B, C. The relative protein expression levels of p-PI3K and p-AKT were quantified in PANC-1 cells. All experiments were repeated at least three times. Data are presented as mean ± SD. *P<0.05 compared to the mock group.
