Table 2.

Down-regulated tissue protein in RHD group compared to control group

Accession number	Protein name	Coverage (%)	RHD group_117: control group_121	p-Value
G3V721	WW domain binding protein 2, isoform CRA_b	13	0.478	< 0.05
Q4FZZ3	Glutathione S-transferase	13.5	0.376	< 0.05
F1LM78	Protein LOC100365958	9.8	0.334	< 0.05
F1LQQ1	Malic enzyme (Fragment)	12.2	0.471	< 0.05
D4A1W8	Microsomal triglyceride transfer protein	3.5	0.388	< 0.05
M0RDH0	Glycine N-methyltransferase	18.8	0.164	< 0.05
F1LR47	Uncharacterized protein	4.8	0.231	< 0.05
G3V6C2	Protein Hgd	16.6	0.211	< 0.05
Q68G44	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (Mitochondrial)	27	0.478	< 0.05
D3ZSF3	Uncharacterized protein	17.8	0.392	< 0.05
Q5M897	Otc protein	20.3	0.264	< 0.05
M0RDC5	Acyl-CoA-binding protein (Fragment)	51.2	0.443	< 0.05
P09034	Argininosuccinate synthase	28.6	0.28	< 0.05
P19112	Fructose-1,6-bisphosphatase 1	8.3	0.442	< 0.05
P32755	4-hydroxyphenylpyruvate dioxygenase	14	0.248	< 0.05
F1LS48	Acetyl-CoA acetyltransferase, cytosolic	2.8	0.205	< 0.05
P21213	Histidine ammonia-lyase	4.9	0.152	< 0.05
P11510	Cytochrome P450 2C12, female-specific	3.7	0.183	< 0.05
P80432	Cytochrome c oxidase subunit 7C, mitochondrial	17.5	0.207	< 0.05
P0CC09	Histone H2A type 2-A	35.4	0.208	< 0.05
Q71US7	Cytochrome P450 2E1 (Fragment)	5.5	0.216	< 0.05
P0C169	Histone H2A type 1-C	35.4	0.098	< 0.05
D3ZJ08	Histone H3	43.4	0.138	< 0.05
P09811	Glycogen phosphorylase, liver form	10.4	0.439	< 0.05
D3ZDW1	Protein Uroc1	6.1	0.347	< 0.05
P12928-2	Isoform L-type of Pyruvate kinase PKLR	6.1	0.327	< 0.05
P22734-2	Isoform 2 of Catechol O-methyltransferase	36.7	0.47	< 0.05
G3V885	Myosin-6	62.1	0.106	< 0.05
P19468	Glutamate--cysteine ligase catalytic subunit	4.6	0.463	< 0.05