Table 3.

Relations among CXCR4, MMP9, TGF-β1, N-cadherin and VEGF expression to clinical pathological factors

	N	CXCR4			P	MMP-9		P	TGF-β1			P	VEGF		P	N-cadherin		P
		+	-			+	-		+	-			+	-		+	-
Sex
Male	44	22	22		0.590	23	21	0.993	18	26		0.609	21	23	0.164	15	29	0.206
Female		9	12			11	10		10	11			12	9		8	13
Age
< 65 years	44	21	23		0.993	22	22	0.590	20	24		0.575	25	19	0.079	17	27	0.164
≥ 65 yesrs	21	10	11			12	9		8	13			8	13		6	15
Clinical stage
I	20	7	13		0.322	12	8	0.048	8	12		0.312	10	10	0.335	8	12	0.191
II	15	7	8			11	4		9	6			10	5		7	8
III	30	17	13			11	19		11	19			13	17		8	22
Lymphatic metastasis
Yes	39	22	17		0.085	17	22	0.085	16	23		0.683	19	20	0.184	13	26	0.190
No	26	9	17			17	9		12	14			14	12		10	16
Local recurrence
Yes	17	9	8		0.614	8	9	0.614	8	9		0.700	8	9	0.208	6	11	0.231
No	48	22	26			26	22		20	28			25	23		17	31
Distant Metastasis
Yes	32	21	11		0.004	19	13	0.261	12	20		0.371	15	17	0.163	11	21	0.202
No	33	10	23			15	18		16	17			18	15		12	21
Brain Metastasis
Yes	11	8	3		0.068	7	4	0.409	5	6		0.861	5	6	0.240	4	7	0.267
No	54	23	31			27	27		23	31			28	26		19	35
Bone Metastasis
Yes	15	12		3	0.004	8	7	0.928	7		8	0.749	7	8	0.217	7	8	0.14
No	50	19		31		26	24		21		29		26	24		16	34