Table 3.

Correlation between clinicopathologic factors and combined tumor markers

Variable	n	Combined 3 markers		P-value
		Negative	Positive
Sum	310
Age (year)
< 65	138	50	88	0.006*
≥ 65	172	38	134
Sex
Male	152	37	115	0.121
Female	158	51	107
Location
Colon	176	47	129	0.451
Rectum	134	41	93
Size (cm)
< 5	174	53	121	0.360
≥ 5	136	35	101
T stage
T1	20	10	10	< 0.001*
T2	58	25	33
T3	166	46	120
T4	66	7	59
N stage
N0	191	91	130	0.113
N1	86	22	64
N2	33	5	28
AJCC stage
I	64	30	34	0.001*
II	127	31	96
III	129	27	92
Differentiation
Well	51	14	37	0.983
Moderate	190	54	136
Poor	69	20	49

^*P < 0.05.