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c-Met overexpression (measured by IHC) and MET gene amplification (measured by FISH) in a cohort of glioblastoma patients
| c-Met IHC | MET FISH | Total | PTEN IHC | Total | ||
|---|---|---|---|---|---|---|
|
|
|
|||||
| Amplification | No amplification | Loss | No loss | |||
| Positive | 7 (5.1%) | 11 (8.0%) | 18 (13.1%) | 1 (0.7%) | 7 (5.1%) | 8 (5.8%) |
| Negative | 0 | 119 (86.9%) | 119 (86.9%) | 19 (13.9%) | 110 (80.3%) | 129 (94.2%) |
| Total | 7 (5.1%) | 130 (94.9%) | 137 (100%) | 20 (14.6%) | 117 (85.4%) | 137 (100%) |
IHC: immunohistochemistry, FISH: fluorescence in situ hybridization.
