Table 2.
Reprimo and hMLH1 gene methylation and protein expression
Group | N | Reprimo methylation rate | Reprimo protein expression | hMLH1 methylation rate | hMLH1 protein expression | Combined rate of methylation | Combined expression rate |
---|---|---|---|---|---|---|---|
Intestinal metaplasia | 50 | 14 (28%) | 16 (32%) | 10 (20%) | 11 (22%) | 17 (34%) | 18 (36%) |
Dysplasia | 50 | 28 (56%) | 30 (60%) | 22 (44%) | 20 (40%) | 38 (76%) | 39 (78%) |
Gastric cancer | 50 | 31 (62%) | 33 (66%) | 24 (48%) | 23 (46%) | 42 (84%) | 41 (82%) |
Normal | 30 | 0 (0%) | 0 (0%) | 1 (3.3%) | 0 (0%) | 1 (3.3%) | 0 (0%) |