Table 4.
Placental pathological lesions by race in women with preterm delivery (32-36 weeks), the Collaborative Perinatal Project, 1959-1966
| Placenta pathological lesions | White Race | African-American | Crude OR | Adjusted OR |
|---|---|---|---|---|
| N (%) | 1,505 (37.4) | 2,564 (62.6) | / | / |
| Placental weight | ||||
| Placental weight < 10th | 250 (16.7) | 533 (20.9) | 1.3 (1.1, 1.6) | 1.3 (1.0, 1.7) |
| PBW ratio > 90th | 452 (30.2) | 554 (21.7) | 0.6 (0.6, 0.7) | 0.8 (0.7, 1.0) |
| Vascular lesions of maternal origin | ||||
| Infarcts in the cut surface | ||||
| Occurrence of vascular infarcts | 216 (14.4) | 230 (9.0) | 0.6 (0.5, 0.7) | 0.8 (0.6, 1.1) |
| Infarct size | 66 (4.4) | 69 (2.7) | 0.6 (0.4, 0.8) | 0.5 (0.3, 0.9) |
| Number of infarcts | 85 (5.7) | 76 (3.0) | 0.5 (0.3, 0.7) | 0.6 (0.3, 1.0) |
| Thrombosis in the cut surface | 101 (6.7) | 56 (2.2) | 0.4 (0.3, 0.5) | 0.8 (0.6, 1.2) |
| Vessel fibroid in the decidua | 56 (3.7) | 47 (1.9) | 0.7 (0.4, 1.0) | 1.1 (0.6, 2.2) |
| Villous lesions of maternal origin | ||||
| Villous infarcts in the intervillous space | 217 (14.4) | 337 (13.2) | 0.9 (0.8, 1.1) | 1.0 (0.7, 1.4) |
| Syncytium-Nuclear clumping in the decidua | 40 (3.5) | 30 (1.4) | 0.4 (0.2, 0.6) | 0.6 (0.3, 1.3) |
| Vascular lesions of fetal origin | 23 (1.5) | 29 (1.1) | 1.0 (0.5, 1.8) | 1.0 (0.4, 2.6) |
| Villous lesions of fetal origin | ||||
| Stromal fibrosis in the terminal villi | 41 (2.7) | 31 (1.2) | 0.4 (0.2, 0.8) | 1.0 (0.4, 2.1) |
| Langerhans layer in the terminal villi | 59 (3.9) | 24 (0.9) | 0.2 (0.1, 0.4) | 0.3 (0.1, 0.7) |
| Marginal insertion of cord | 84 (5.6) | 96 (3.8) | 0.6 (0.5, 0.9) | 0.9 (0.5, 1.4) |
| Calcification throughout the cut surface | 128 (8.5) | 195 (7.6) | 0.6 (0.5, 0.8) | 0.8 (0.5, 1.2) |
| Hemorrhage | ||||
| Occurrence of hemorrhage | 179 (11.9) | 163 (6.4) | 0.6 (0.4, 0.7) | 0.9 (0.6, 1.3) |
| Old hemorrhage in the maternal surface | 136 (9.0) | 98 (3.8) | 0.2 (0.1, 0.4) | 0.6 (0.2, 1.7) |
| Thrombosis in the intervillous space | 208 (13.8) | 147 (5.7) | 0.4 (0.3, 0.5) | 0.7 (0.5, 1.0) |
| Inflammatory cell infiltration | ||||
| Fetal neutrophilic infiltration | 91 (6.1) | 227 (8.9) | 1.5 (1.2, 1.9) | 1.7 (1.1, 2.4) |
| Maternal neutrophilic infiltration | 190 (12.6) | 384 (15.0) | 1.2 (1.0, 1.5) | 1.1 (0.8, 1.4) |
| Maternal lymphocytic infiltration | 16 (1.1) | 37 (1.4) | 1.4 (0.8, 2.5) | 1.4 (0.6, 3.5) |
| Meconium | 68 (4.5) | 225 (8.8) | 2.2 (1.6, 3.0) | 1.1 (0.8, 1.7) |
PBW ratio: Placenta-to-birth weight ratio. Crude OR. Unadjusted logistic model. Reference group: white women. Adjusted OR. Logistic model adjusted for maternal age, education, marital status, parity, socioeconomic status, pre-pregnancy body mass index, gestational age, and study center. Bold font: P < 0.05.