Table 3.
Logistic regression analyses of associations between BCL2 rs17757541 C>G polymorphism and risk of CAD
| Genotype | Cases (n = 826)a | Controls (n = 1153) | Crude OR (95% CI) | P | Adjusted ORb (95% CI) | P | ||
|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||
| N | % | n | % | |||||
| BCL2: rs17757541 C>G | ||||||||
| CC | 575 | 69.61 | 823 | 72.19 | 1.00 | 1.00 | ||
| CG | 220 | 26.63 | 294 | 25.79 | 1.07 (0.87-1.31) | 0.511 | 1.05 (0.83-1.31) | 0.705 |
| GG | 31 | 3.75 | 23 | 2.02 | 1.93 (1.11-3.34) | 0.019 | 1.87 (1.03-3.41) | 0.041 |
| CG+GG | 251 | 30.39 | 317 | 27.81 | 1.13 (0.93-1.38) | 0.213 | 1.11 (0.89-1.38) | 0.362 |
| CC+CG | 795 | 96.25 | 1,117 | 97.98 | 1.00 | 1.00 | ||
| GG | 31 | 3.75 | 23 | 2.02 | 1.89 (1.10-3.27) | 0.022 | 1.85 (1.02-3.36) | 0.044 |
| G allele | 282 | 0.17 | 340 | 0.15 | ||||
a
The genotyping was successful in 826 (100%) CAD cases, and 1140 (98.9%) controls for BCL2 rs17757541 C>G;
b
Adjusted for age and sex.
Bold values are statistically significant (P < 0.05).