Table 2.
Characteristics between patients with HCC and control subjects
| Characteristics | Patients N=274 | % | Controls N=328 | % | t test or χ2 test | P value | OR (95% CI) | P value |
|---|---|---|---|---|---|---|---|---|
| Age, years | 57.35±12.65 | 54.24±11.45 | 3.16 | 0.001 | ||||
| <55 | 121 | 44.16 | 179 | 54.57 | 1.0 (Ref.) | - | ||
| ≥55 | 153 | 55.84 | 149 | 45.43 | 6.47 | 0.01 | 1.52 (1.09-2.13) | 0.01 |
| Gender | ||||||||
| Female | 61 | 22.26 | 120 | 36.59 | 1.0 (Ref.) | - | ||
| Male | 213 | 77.74 | 208 | 63.41 | 14.56 | <0.001 | 2.01 (1.38-2.95) | <0.001 |
| Smoking status | ||||||||
| No | 143 | 52.19 | 188 | 57.32 | 1.0 (Ref.) | - | ||
| Yes | 131 | 47.81 | 140 | 42.68 | 1.59 | 0.21 | 1.23 (0.88-1.72) | 0.21 |
| Alcohol status | ||||||||
| No | 113 | 41.24 | 195 | 59.45 | 1.0 (Ref.) | - | ||
| Yes | 161 | 58.76 | 133 | 40.55 | 19.81 | 0.001 | 2.09 (1.49-2.93) | <0.001 |
| Viral infection | ||||||||
| Both negative | 43 | 15.69 | 287 | 87.50 | 1.0 (Ref.) | - | ||
| HBV positive | 168 | 61.31 | 34 | 10.37 | 32.98 (19.70-55.46) | <0.001 | ||
| HCV positive | 59 | 21.53 | 7 | 2.13 | 56.26 (23.28-152.98) | <0.001 | ||
| Both positive | 4 | 1.46 | 0 | 0 | 311.94 | <0.001 | - | - |
| Liver cirrhosis | ||||||||
| No | 210 | 76.64 | ||||||
| Yes | 64 | 23.36 | ||||||
| Child-Pugh classification | ||||||||
| A | 43 | 15.69 | ||||||
| B | 97 | 35.40 | ||||||
| C | 135 | 49.27 | ||||||
| α-fetoprotein, ng/ml | ||||||||
| <100 | 119 | 43.43 | ||||||
| 100-400 | 49 | 17.88 | ||||||
| >400 | 106 | 38.69 |