Table 3.

Association between IL-10 -1082A/G, -819T/C, and -592A/C gene polymorphisms and risk of diabetic nephropathy

Model	IL-10	Patients	%	Controls	%	OR (95% CI)1	P value
	-1082A/G
Codominant	GG	66	38.37	163	47.38	1.0 (Ref.)	-
	GA	80	46.51	153	44.48	1.29 (0.85-1.95)	0.2
	AA	26	15.12	27	7.85	2.38 (1.23-4.57)	0.05
Dominant	GG	66	38.37	163	47.38	1.0 (Ref.)	-
	GA+AA	106	61.63	180	52.33	1.47 (1.05-2.16)	0.04
Recessive	GG+GA	146	84.88	316	91.86	1.0 (Ref.)	-
	AA	26	15.12	27	7.85	2.08 (1.12-3.85)	0.01
	-819T/C
Codominant	TT	57	33.14	127	36.92	1.0 (Ref.)	-
	TC	77	44.77	150	43.60	1.14 (0.74-1.77)	0.53
	CC	38	22.09	67	19.48	1.26 (0.74-2.16)	0.36
Dominant	TT	57	33.14	127	36.92	1.0 (Ref.)	-
	TC+CC	115	66.86	217	63.08	1.18 (0.79-1.77)	0.40
Recessive	TT+TC	134	77.91	277	80.52	1.0 (Ref.)	-
	CC	38	22.09	67	19.48	1.17 (0.73-1.87)	0.49
	-592A/C
Codominant	AA	67	38.95	132	38.37	1.0 (Ref.)	-
	AC	79	45.93	155	45.06	1.01 (0.66-1.53)	0.98
	CC	26	15.12	57	16.57	0.89 (0.50-1.61)	0.7
Dominant	AA	67	38.95	132	38.37	1.0 (Ref.)	-
	AC+CC	105	61.05	212	61.63	0.98 (0.66-1.45)	0.9
Recessive	AA+AC	146	84.88	287	83.43	1.0 (Ref.)	-
	CC	26	15.12	57	16.57	0.90 (0.52-1.52)	0.67

¹Adjusted for age, gender, BMI, hypertension, triglyceride, total cholesterol, high density lipoprotein, low density lipoprotein and creatinine.