Table 2.
Genotypes and alleles distribution of ABCB1 C1236T and C3435T polymorphisms
| Genotype/allele | Case (n, %) | Control (n, %) | χ2 | P value | OR (95% CI) |
|---|---|---|---|---|---|
| C1236T | |||||
| CC | 27 (23.9) | 25 (21.6) | - | - | 1.000 |
| CT | 53 (46.9) | 60 (51.7) | 0.359 | 0.549 | 0.82 (0.42-1.58) |
| TT | 33 (29.2) | 31 (26.7) | 0.001 | 0.969 | 0.99 (0.47-2.05) |
| C | 107 (47.3) | 110 (47.4) | - | - | 1.000 |
| T | 119 (52.7) | 122 (52.6) | 0.000 | 0.988 | 1.00 (0.70-1.45) |
| C3435T | |||||
| CC | 43 (40.0) | 28 (24.1) | - | - | 1.000 |
| CT | 56 (51.3) | 61 (52.6) | 2.859 | 0.091 | 0.60 (0.33-1.09) |
| TT | 14 (17.7) | 27 (23.3) | 7.258 | 0.007 | 0.34 (0.15-0.75) |
| C | 142 (62.8) | 117 (50.4) | - | - | 1.000 |
| T | 84 (37.2) | 115 (49.6) | 7.165 | 0.007 | 0.60 (0.42-0.87) |