Figure 6. N‐acetylcysteine increased the BK_Ca channel β1 subunit and BK_Ca channel in uterine arteries of high‐altitude pregnant sheep .

Uterine arteries isolated from pregnant sheep acclimatized to long‐term high‐altitude hypoxia were treated under 10.5% O₂ for 48 h in the absence or presence of 1 mm N‐acetylcysteine (NAC). A, protein abundance of the β1 subunit was determined by Western blot. Data are means ± SEM of 4–5 tissues from 4–5 animals of each group. Data were analysed with t test. *P < 0.05, +NAC vs. –NAC. B, BK_Ca currents in smooth muscle cells were recorded. Data are means ± SEM of six cells from five animals of each group. Data were analysed with repeated measures ANOVA. *P < 0.05, +NAC vs. –NAC.