Table 1.

Summary of HFpEF Diagnosis Guidelines

Guidelines	Diagnosis
ESC (9)	The following 4 criteria are required: 1) symptoms typical of HF; 2) signs typical of HF; 3) normal or only mildly reduced LVEF and LV not dilated; and 4) relevant structural heart disease (LV hypertrophy/LA enlargement) and/or diastolic dysfunction
ACC/AHA–HFpEF (6)	Diastolic HF. Multiple criteria have been used; exclude other potential noncardiac causes of symptoms suggestive of HF.
ACC/AHA–EF 41%-49%	Borderline or intermediate EF; these patients have similar characteristics, treatment patterns, and outcomes to those with HFpEF
ACC/AHA– improved EF	Patients previously with HFrEF; improved or recovered EF clinically distinct from patients with preserved or reduced EF.
HFSA (7)	Patients with EF ≥50% with symptoms suggestive of HF. Use echocardiography, ECG, stress imaging, or cardiac catheterization to distinguish HF with preserved LVEF and other cardiac disorders.

ACC = American College of Cardiology; AHA = American Heart Association; ECG = electrocardiogram; ESC = indicates European Society of Cardiology; HF = heart failure; HFpEF = heart failure with preserved ejection fraction; HFrEF = heart failure with reduced ejection fraction; HFSA = Heart Failure Society of America LA = left atrial; LV = left ventricle; LVEF = left ventricular ejection fraction.