Table 1. Plasma propofol concentration (μg/ml) in the ewes and the fetuses.
Time (minutes) | Ewes (μg/ml) | Fetuses (μg/ml) | Fetal: maternal ratio |
---|---|---|---|
Baseline | BLQ | BLQ | - |
5 | 5.43±2.06 | 0.35±0.21 | 0.07±0.04 |
15 | 6.82±2.57 | 0.68±0.31 | 0.11±0.07 |
25 | 8.71±1.60 | 0.95±0.41 | 0.11±0.04 |
60 | 9.18±3.25 | 1.31±0.51 | 0.15±0.06 |
75 | 4.47±1.95 | 0.81±0.25 | 0.20±0.06 |
100 | 3.33±1.75 | 0.48±0.12 | 0.16±0.04 |
110 | 3.05±1.56 | 0.40±0.15 | 0.14±0.06 |
150 | 2.42±0.93 | 0.36±0.15 | 0.15±0.05 |
180 | 0.70±0.41 | 0.20±0.06 | 0.37±0.22 |
Samples were collected simultaneously from the maternal and fetal femoral arterial lines. Data show as mean ± SD. BLQ = below lower limit of quantification for propofol level (< 0.05 ng/ml).