Figure. Comparison of identified Pen a 1 IgE-binding epitopes with homologous sequences in other allergic tropomyosins. Pen a 1 (Genbank accession number AAZ76743) from shrimp Penaeus aztecus, Pen m 1 (BAF47262) from shrimp Penaeus monodon, Pan b 1(CBY17558) from shrimp Pandalus borealis, Cra c 1 (ACR43473 ) from shrimp Crangon crangon, Mel l 1 (AGF86397) from prawn Melicertus latisulcatus, Mar c 1 (ADC55380) from prawn Macrobrachium rosenbergii, Hom a 1 (AAC48288) from lobster Homarus americanus, Pan s 1 (AAC38996) from Lobster Panulirus stimpsoni, Por p 1 (AGE44125) from crab Portunus pelagicus, Cha f 1 (AAF35431) from crab Charybdis feriatus, Hel as 1 (CAB38044.1) from snail Helix aspersa, Ore m 4 (AFV53352) from fish Oreochromis mossambicus, Der p 10 (CAA75141) from mite Dermatophagoides pteronyssinus, Der f 10 (BAA04557) from mite Dermatophagoides farinae, Blo t 10 (ABU97466) from mite Blomia tropicalis, Lep d 10 (CAB71342) from mite Lepidoglyphus destructor, Tyr p 10 (AAT40866) from mite Tyrophagus putrescentiae, Bla g 7 (AAF72534) from cockroach Blattella germanica, Per a 7 (AAD19606) from cockroach, Chi k 10 (CAA09938) from Midge Chironomus kiiensis, Ani s 3 (CAB93501) form parasite Anisakis simplex, Asc l 3 (ACN32322) from parasite Ascaris lumbricoides, Lep s 1 (CAC84590) from silverfish Lepisma saccharina. IgE epitopes on the studies of Pen a 1 and Pen m 1 are shaded. Sequences that are aligned with the identified Pen a 1 IgE epitopes are boxed. The numbers in the parentheses indicated the percentages of identity as compared to the sequence of Pen a 1. ^*Let v1 and Pen a 1 have identical sequence.