Table 1.
Summary of Myc, MycVD, and Myc/APOZ Engineered Tumors.
Number of Mice with Tumor / Total Number of Mice | Tumor Latency (Days) | Median Survival (Days) | Pathology | |
---|---|---|---|---|
Myc | 25/25 | 16, 24, 26, 26, 27, 27, 28, 31, 32, 33, 33, 33, 34, 36, 38, 40, 40, 40, 41, 42, 43, 52, 56, 56, 59 | 34 | LC/A, Myc/G3 MB |
MycVD | 6/13 | 61, 70, 77, 89, 109, 119 | 83 | Neuroepithelial proliferation of unclassified type |
Myc/ΔPOZ | 10/10 | 22, 42, 44, 48, 49, 60, 61, 62, 69, 74 | 54.5 | PNET-like tumor with LC/A; unclassified type |
LC/A = Large cell/anaplastic, G3 MB = Group3 medulloblastoma, PNET = Primitive neuroectodermal tumor, median survival was calculated based on the number of mice that develop one tumor per animal.