Table I.
Reference | Age/sex | Pathogen | Anatomic site | Underlying condition | Surgical treatment | Anti-NTM therapy | Outcome |
---|---|---|---|---|---|---|---|
Phoa et al. [70] | 66/M | M. scrofulaceum | Wrist | DM | None | KAN, EMB, and ETH | Improved clinically |
Satti et al. [84] | 52/M | M. fortuitum | Bone marrow | DM | None | AMK and CIP | Cured |
Argiris et al. [188] | 37/M | MAC | Bone marrow | DM, ESRD, renal transplant | None | AZM and EMB | Died |
Baylor et al. [189] | 39/M | MAC | Humerus, tibia, and fibula | DM, schizophrenia | Surgical debridement | STR, CFZ, INH, EMB, RFP, PZA, CLR, and AMK | Cured |
Iyengar et al. [95] | 58/F | M. chelonae | Finger metacarpal heads | DM, ESRD | Incision for drain, surgical debridement | CFZ and CLR | Cured |
Conejero et al. [190] | 76/F | M. chelonae | Metatarsal and calcaneus | DM and RA | None | Intravenous IPM, CLR, and LVX | Cured |
Halleran et al. [191] | 61/M | MAC | Wrist | DM, hypertension | Aspiration | INH and RFP | Unresolved |
Suzuki et al. [8] | 67/M | MAC | Spine, ribs, and pelvis | DM | Surgical debridement | RFP, EMB, CLR, CS, and STR | Cured |
This study | 69/M | M. intracellulare | Humerus and ribs | DM | Anti-mycobacterial chemotherapy | CLR, EMB, and MXF | Died |
AMK, amikacin; AZM, azithromycin; CFZ, clofazimine; CIP, ciprofloxacin; CLR, clarithromycin; CS, cycloserine; EMB, ethambutol; ESRD, end-stage renal disease; ETH, ethionamide; INH, isoniazide; IPM, imipenem; KAN, kanamycin; LVX, levofloxacin; MAC, M.avium-intracellulare complex; MXF, moxifloxacin; PZA, pyrazinamide; RA, rheumatoid arthritis; RFP, rifampicin; STR, streptomycin.