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. 2015 Nov 23;291(3):1053–1063. doi: 10.1074/jbc.M115.673129

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FIGURE 1. — Skin patterns of zebrafish. A, wild type; B, leopard mutant (cx41.8^−/−, leo^t1 allele, null mutant); C, leopard mutant (cx41.8^tq270/tq270, leo^tq270 allele, Cx41.8I203F); D, luchs mutant (cx39.4^−/−; knock-out of cx39.4 by TALEN); E, luchs/leopard double homozygous mutant (cx39.4^−/−;cx41.8^−/−); F, connexin topology sketch highlighting Cx41.8 mutants used in this study. G, summary of the transgenic experiments; H–J, transgenic zebrafish: Tg(mitfa-cx41.8I203F)cx41.8^−/− (H), Tg(mitfa-cx41.8M7)cx41.8^−/− (I), and Tg(mitfa-cx41.8M7)cx41.8^+/+ (J). H′–J′, magnified images of H–J. Scale bar, 5 mm.