Electrophysiological analysis of homomeric-homotypic gap junctions. Junctional current traces of homotypic gap junctions of Cx41.8 (A), Cx39.4 (B), Cx41.8I203F (C), and Cx41.8M7 (D). A′ and B′, plots of normalized steady state junctional conductance versus transjunctional voltages (A′, n = 24; B′, n = 30). For these experiments, 40 ng of mRNA for Cx41.8 or its mutant or 5 ng of mRNA for Cx39.4 was injected into each oocyte.