FIGURE 10.
Inhibition of PbGH5A with active-site affinity labels. A and C, inhibition of PbGH5A with compound 1. A, plot of reaction velocity versus time at different inhibitor concentrations. C, plot of pseudo first-order rate constants versus inhibitor concentration. B and D, inhibition of PbGH5A with compound 2. B, plot of reaction velocity versus time at different inhibitor concentrations. D, plot of pseudo first-order rate constants versus inhibitor concentration. Error bars represent the fitting error of the exponential decay function. E, chemical structure of inhibitor compound 1. F, chemical structure of inhibitor 2.