TABLE 3.

eIF4G and eIFiso4G2 support Ω-mediated translation

Mutant line	Luc mRNA		Ω-Luc mRNA		Ω dependence
	Luciferase/qPCRa	Relative expression	Luciferase/qPCRa	Relative expression
WT	1,025,659	1	331,629	1
eifiso4e	1,122,767	1.09	1,181,881	3.56	0.307
eif4g	4,404	0.00429	56.2	0.000169	25.3
eifiso4g1	270,204	0.263	45,562	0.137	1.92
eifiso4g2	71,921	0.0701	883	0.00266	26.3
eifiso4g1/2	28,821	0.0281	10,844	0.0327	0.859

^a Luciferase expression and qPCR data are taken from Tables 1 and 2 and Fig. 2.