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. 2015 Nov 24;291(3):1514–1528. doi: 10.1074/jbc.M115.684399

FIGURE 2.

FIGURE 2.

1α,25(OH)2D3 increases cellular OCR in primary cultures of the human skeletal muscle cells. A, OCR in the presence of 1α,25(OH)2D3 (n = 5) or vehicle (n = 8) and various inhibitors. B, effect of 1α,25(OH)2D3 or vehicle on basal respiration. C, effect of 1α,25(OH)2D3 or vehicle on maximal respiration. D, effect of 1α,25(OH)2D3 or vehicle on coupled respiration. E, effect of 1α,25(OH)2D3 or vehicle on reserve capacity. F, effect of increasing concentrations of 1α,25(OH)2D3 on maximal respiration (vehicle (n = 3), 1 × 10−11 m (n = 4), 1 × 10−10 m (n = 4), 1 × 10−9 m (n = 3). p values (compared with vehicle) for each concentration of 1α,25(OH)2D3 are as follows: 1 × 10−11 m, p = 0.19, 1 × 10−10 m, p = 0.08, 1 × 10−9 m, p = 0.04). All values in A–F are expressed as mean ± S.E. (error bars).