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1α,25(OH)2D3 increases mitochondrial volume and fragmentation. A and B, effect of 1α,25(OH)2D3 or vehicle on mitochondrial volume density (mitochondrial volume normalized to total cell volume) (A) and mitochondrial morphometry (aspect ratio and form factor) (B). C, effect of 1α,25(OH)2D3 or vehicle on mitochondrial ultrastructure. For all measurements, the number of replicates was 10. Values are expressed as mean ± S.E. (error bars). *, p ≤ 0.05.
