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Gross and microscopic characteristics of the tumor and sickle cell status (A–E). A, Note that the tumor is located in the cortico-medullary region, with lymph node hilar metastasis. B and C, Glandular differentiation and desmoplastic stroma with inflammatory cells in the medullary carcinoma. D, Drepanocytes identified between and at the periphery of the carcinoma. E, Electrophoretic analysis documented high level of mutated Hemoglobin (S).
