Table 3.

Recommendations for Smoking Cessation

2005 Recommendation	2011 Focused Update Recommendations	Comments
Class I
	1. Patients who are smokers or former smokers should be asked about status of tobacco use at every visit (25-28). (Level of Evidence: A)	New recommendation
	2. Patients should be assisted with counseling and developing a plan for quitting that may include pharmacotherapy and/or referral to a smoking cessation program (26,29). (Level of Evidence: A)	New recommendation
Individuals with lower extremity PAD who smoke cigarettes or use other forms of tobacco should be advised by each of their clinicians to stop smoking and should be offered comprehensive smoking cessation interventions, including behavior modification therapy, nicotine replacement therapy, or bupropion. (Level of Evidence: B)	3. Individuals with lower extremity PAD who smoke cigarettes or use other forms of tobacco should be advised by each of their clinicians to stop smoking and offered behavioral and pharmacological treatment. (Level of Evidence: C)	Modified recommendation (wording clarified and level of evidence changed from B to C).
	4. In the absence of contraindication or other compelling clinical indication, 1 or more of the following pharmacological therapies should be offered: varenicline, bupropion, and nicotine replacement therapy (30-33). (Level of Evidence: A)	New recommendation

PAD indicates peripheral artery disease.